Pamene katulutsidwe, puloteniyo imamatirira ku physiologically active BNP (77th mpaka 108th amino acid) ndi n-terminal fragment NT-proBNP (1st mpaka 76th amino acid).Pamene BNP, yomwe ndi 32 amino acid yaitali, imatulutsidwa m'magazi, imamangiriza ku zolandilira zake (NPRA ndi NPRB) ndikuwongolera kuthamanga kwa magazi kudzera m'njira zosiyanasiyana.NT-proBNP, yomwe ndi 76 amino acid yaitali, ilibe zochitika zamoyo, koma chifukwa imakhala ndi theka la moyo wautali kuposa BNP, imakhala yabwino kwambiri ngati chizindikiro cha matenda osiyanasiyana a mtima.Poyezetsa ziweto, kuchuluka kwa magazi a NT-proBNP mwa agalu ndipamwamba kuposa 900 pmol/L, ndipo amphaka ndi apamwamba kuposa 270 pmol/L, ndipo pali chiopsezo chachikulu cha matenda okhudzana ndi mtima.Komabe, ziyenera kukumbukiridwa kuti chifukwa NT-proBNP imachotsedwa ndi impso, pamene chiweto chikudwala matenda okhudzana ndi impso, ndende ya NT-proBNP m'thupi idzawonjezekanso ndipo zotsatira zabodza zidzawonekera pa mayesero.
Izi utenga fluorescence immunochromatography kudziwa zili fNT-proBNP mu seramu/plasma quantitatively.Mfundo yofunikira: Pali mizere ya T ndi C pa nembanemba ya nitric acid fiber motsatana, ndipo mzere wa T umakutidwa ndi antibody omwe amazindikira mwapadera fNT-proBNP.Pad yophatikizika imapopera ndi fulorosenti ina ya nanomaterial yotchedwa antibody b yomwe imatha kuzindikira FDT-probNP.Muchitsanzo, FDT-probNP choyamba imaphatikizana ndi nanomaterial otchedwa antibody b kupanga zovuta, ndiyeno kumtunda wa chromatography, zovutazo zimaphatikizana ndi T-line antibody A kupanga masangweji.Pamene chisangalalo cha kuwala walitsa, ndi nanomaterial zimatulutsa fluorescence siginecha.Mphamvu ya siginecha imagwirizana bwino ndi kuchuluka kwa fNT-proBNP pachitsanzo.
Chiyambireni kukhazikitsidwa kwake, fakitale yathu yakhala ikupanga zinthu zapamwamba kwambiri padziko lonse lapansi ndikutsatira mfundoyi
za khalidwe poyamba.Zogulitsa zathu zapeza mbiri yabwino pamsika komanso kukhulupirika pakati pa makasitomala atsopano ndi akale..